Analgesics are the most widely used OTC medicines and the market is flooded with lots of analgesics available in single as well as combination forms. All of these available products are not useful, and hence it is very important for the consumer to identify the harmful, irrational and useful analgesics and choose the right product for his/her condition.
The following information will give a brief account of the analgesics which should not be used as they offer no special benefits over the rational analgesic product.
I Analgesics that are harmful
a) Analgin (Dipyrone) and its combinations
The use of
Analgin and its combinations can cause severe blood disorders, the appearance
of which is sudden and unpredictable. The risk of such serious adverse
effects of analgin and the availability of other safer and equally effective
analgesics (e.g., aspirin, paracetamol) do not justify the use of analgin.
It has been banned in many countries all over the world. Examples of brand
products of Analgin (single and combination) are listed below:
Baralgan has been since banned by an order of the Supreme Court of India.
b) Oxyphenbutazone and Phenylbutazone
The use of oxyphenbutazone and phenylbutazone as anti-inflammatory drugs is restricted to only hospital treatment of severe conditions like ankylosing spondylitis.
serious adverse effects such as peptic ulcer, blood disorders, kidney
and liver problems, and hence their use for minor inflammatory ailments
is not recommended. They have been banned in many countries all over the
world and safer alternatives such as aspirin, paracetamol and ibuprofen
are being recommended. Examples of brand products of oxyphenbutazone and
phenylbutazone (single and combination) are:
II Irrational Analgesic Combinations
Analgesics plus Caffeine: This combination unnecessarily increases
the cost of the product. Beside caffeine has got no analgesic or anti-inflammatory
effect and it may itself induce headache in excess doses or on sudden
stopping of the medicine. Examples of marketed products are:
Analgesics plus Metoclopramide: In these products metoclopramide
is claimed to help produce a more rapid effect by facilitating the absorption
of analgesics. However, this is not true. Moreover, metoclopramide causes
serious adverse effects like drowsiness, fatigue, etc. Hence this combination
is useless, irrational and expensive. Examples of marketed products are:
Analgesics plus Sedatives: This combination can cause excessive
sedation (sleeping effect) which can be dangerous. Hence it is an irrational
and expensive combination. Examples of marketed products are:
III Useless Analgesics
Enzymes and Chymotrypsin as Anti-inflammatory Agents: Although
available in the market, the use of chymotrypsin and other enzymes in
the treatment of swelling and pain has not been proven adequately. Examples
of marketed products are:
C. Satyamala, Nirmala Sundaram and Nalini Bhanot: